I always use Symantec Endpoint Protection 11.0 on Vista, have not installed 2008 to test it, but should work. Reason I like it is because no serial, hacks required.
I use Kaspersky 2009 Internet Security on server 2008. I use Vista Ultimate Token.dat and on server 2008, install KIS and replace the vista token.dat back with the server 2008 std. token.dat and than Viola!
Antivirus hi there, I use NOD32 antivirus combined with the built in firewall (Server 2008 Standard). Nice combination
I'd prefer NOD32 AV + Comodo Firewall, else both Comodo AV(when it is v3) + Comodo Firewall (+ Comodo BOClean). Eset Smart Security did not install. Frankly, any security is much like a lock at the doorway, with real thieves coming in no problem if they wish to come in. So be alert . - Roman.
I use Symantec Endpoint Protection v11.0.3001.2224 here. The anti-virus is quite good, having found at least a dozen questionable files that I've had on my HD for years. The firewall seems pretty sound too, and pop-ups are minimal. There is an anti-malware module in the suite, but it doesn't seem to work under W2K8. I know Symantec and Norton have a bad rap as resource intensive pigs, but I can assure you that SEC is extraordinarily easy on resources, and trouble free. My other choice (with the exception of one nasty bug) is/will be Outpost Security Pro 2009. The firewall is second to none, and the A/V section seems fairly good as well. However, on both Vista and W2K8, it has a nasty habit of bringing the network and operating system to a complete stand still at least several times a day. The only option is to do a dirty shutdown and reboot. This suite is also very light on resources. If they get this bug sorted out, it'll be my number one. I've spent a few days with Comodo Security, but IMHO, there is too much user intervention required for the Defense/Intrusion Prevention module.
make sure you only install the AV/ASPY no proactive threat or Net/app control on SEP. Make sure its At least MR3 maybe wait for MR4. SMB2 shares would get killed with older versions or drop back to smb1