I never use my touch-screen, so I disabled it via the device manager. Is there any problem with doing so? Never had a touch-screen before, and I'm not sure I'd ever get one again on purpose. (Got this one by default config).
No problem with such action! Just, in case the Mouse will be down and/or didn't works anymore, you could just enable the touch screen and use your finger('s) instead of the Mouse. Better, you didn't un-install the Touch Screen Driver!
And the good news will be your battery is going to last longer, because touch screen feature is a huge battery drainer
I like touch screen for flexibility, most especially, when you are lying in bed and want to use your system.
I guess that makes sense, but I have a backlit keyboard and I'm a touch-typist, so for me, the feature is more of an annoyance if I have to keep wiping fingerprints off the screen, etc.