i worked remote support for customers of QVC and they had a Fonts package software.. you have similar ?
Use SpaceSniffer to figure out which files takes so much space. Dont forget to run it as Administrator in order to avoid showing "access denied" errors.
I don't believe that your Fonts folder actually is 35GB in size. Look at the amount of bytes in parenthesis...notice anything weird? The comma placements are off... six numbers and a comma, two numbers and a comma, and then three numbers at the end. Looks to me as if your folder isn't actually 35GB but you just happened to find a nice little bug in explorer.exe which displays improper comma placements in numbers and because of that reported the wrong folder and file sizes. If I were you I'd contact Microsoft and show them this image and see what they have to say about it, because it looks like something which definitely needs a hotfix created and deployed to correct the problem that you're having.
This will send the result to a file called fontsfolder.txt on c:\ dir /a C:\Windows\Fonts > c:\fontsfolder.txt