My new USB drive is in FAT32. If I plan to use this for a Windows 10 install drive, do I need to format it to something else?
it needs to be bootable and formatted properly. Mr.X has post probably one of the best if not the best solution available today.
Rufus does everything on its own. Just make sure you manually select GPT partition if you are using a hdd with GPT partitions, or else leave at default.