I have: en_windows_10_pro_10240_x64_dvd (3.71 Gbytes) Rufus 2.2 (Latest version) 16 Gbtye SanDisk Cruzer Thumb Drive I made a Win7 USB boot drive last week, so the only thing new here is the Win10 .ISO. It's failed half-way through the process four (4) times. I take the standard, default settings. Is there something special one has to do with Win10? I've done some research and I find no evidence that there is something special about Win10.