My Logitech MX518 mouse disconnects and reconnects frequently (the device disconnect/reconnect Windows sounds play). When this happens, the mouse stops working for about 2 seconds. When it was plugged into the back of my motherboard, Logitech's SetPoint software would lose track of my settings until I opened and closed the SetPoint window. Now that I've been running the mouse plugged into a front USB port, I don't lose the settings, but the 2 second drop-outs are still very annoying (especially for gaming). As for my Steelsound 5Hv2 USB headset, while playing Battlefield: Bad Company 2, I get infrequent "lag outs" that cause the microphone to stop working with either Steam voice chat or xfire voice chat. To get it working again, I have to exit the game/chat and restart xfire. By "lag outs", I mean the game will start running at less than 1fps, the audio gets so choppy you can't understand anything, and then maybe 20 seconds later it goes back to normal—aside from the microphone no longer working in whatever voice chat I was using. System specs: OS: Windows 7 x64 SP1 Mobo: ASUS M4A79XTD EVO AM3 790X ATX CPU: AMD Phenom II X2 550 Black Edition Callisto 3.1GHz (unlocked to 4 cores) RAM: G.SKILL Ripjaws Series 4GB (2 x 2GB) DDR3 1600 Video: EVGA 01G-P3-N959-TR GeForce 9500 GT 1GB PSU: CORSAIR CMPSU-750TX 750W HDD: WD1001FALS 1TB No overclocking.