By the specs i'm guessing your card is a retail HD6450(bad card if you're looking for performance really). Don't know why speccy reads it like an R5 230(i guess, maybe a 220), but then again, I had a roommate who's laptop's HD6470(without a proper amd driver) appeared as an HD7470(with any proper driver). Have you tried a clean gpu driver installation? Cleaning up with display driver uninstaller?
In my attempts to find out what exactly is happening... I discovered something else. The above only applies if I launch Notepad the "normal" way. If I launch Notepad as admin, the problem is gone. One step closer...
WOW, be sure you keep up to date.. no wonder you have ATI.. I use Nvidia.. But you got resolved. ATGPUD2003
In other words, a rebranded HD6450. The entire Rx 200 series is a rebrand(except the 290 and 290X, those are...WERE actually new). That's not the point of the thread, tho. You explained in unnecessary detail that you're using the 15.7.1 driver, ok, but you didn't say if you've performed a clean install of it. I'm beginning to think your "problem" is very similar to a refresh of the desktop(you know, that unexplainable habit of rightclick->refresh on the desktop). Don't know how it's related to launching notepad as admin.
Disable the animation effect shown in the attachment and see if the annoying icons refresh is still happening.
Folders are refreshing showing generic folder icon and shotcuts are also showing the generic unknown file icon Only Trash icon is not flickering because it doesn't change icon while refreshing. Did you rebuild icons cache? Are you using some programs related to icons?
I presented the problem on 3 forums (including a PC Helpforum in my own language). Nothing. Nada. Which was to be expected. This is/was a complex problem. You need to know exactly where to look. I didn't. Still don't. And apparently nobody does. So, after many frustrating hours of trying everything I could think of, I decided it was time to initiate plan B. I created a new (admin) user account. Transfered as much as possible from the old account and rebuilt the rest. And guess what. The problem is gone. Not a fix, unfortunately, but a bypass. If you can't eliminate the problem, go around it. Now all that's left is to make sure everything is running the way it's supposed to, before removing the old account. I thank those of you who took the trouble to come up with suggestions. None of them worked, but it was worth a shot.