Normally UWT 2.0 also works with x64. I have used it with my x64 and x86. Nice list btw, gonna check some of them out. gen
You don't learn anything with tweakers, I prefer tweak the system myself. Anyway Tune-up utilities is a must to keep the system's health and have some tweaks too.
I try the tweakers out to see if there might be some tweaks I don't know about yet. Then I search for the manual method.