what edition of Windows Vista are you using? Windows Loader only works with Starter, Home (Basic & Premium), Business & Ultimate editions of Vista
When you load DAZ 2.2.2, the product key shown in its window will say "Trial". When you click the "Trial" button, it will scan and then display a permanent product key. After that's done, close the window. Windows Vista should now show as being activated.
I used DAZ loader 2.2.2 again yesterday on a clean untouched copy of Windows Vista Business SP2 64-bit. It loaded and worked fine.