The tool's creator originally posted it in the Windows 10 subreddit simply as a way for inexperienced users to opt out of Microsoft tracking. I'm sure they are just false positives. The tool is also open source, so people can check if there's any malicious code.
Good effort and thanks for sharing. I don't have github or reddit account to directly contact the author and I'm lazy to create one just to pull request. If you can tell him to come here, it's a good place for this kind of stuff. I don't agree with the fact it is for inexperienced users. The GUI doesn't just tell enough about what it does. IMHO, users need more informations about what each option implies, why users would need it or NOT, warning if needed (what can't be revert or not). I would like a info panel when one select an option (don't know if it's possible with wxPython, it implies using other GUI elements). A good start, second to me, would take inspiration from the good old XP-antipsy and its profile management. I would need something with more detailed and separated options that can detect option state on OS. Please report this post to the author.
I'm mostly a lurker, but here I am. As for your points, I've added tooltips. EDIT: The reason that I say it's for "inexperienced users" is that it's a lot easier to download a file and run it and select a few checkboxes than it is to mess with the registry.