I had asked couple of times if there was a way to make Autocad works on Windows 10 TP 10041 Now Autocad 2016 released and it works on Windows 10. FYI
I tried running Autodesk Inventor 2013 and it wouldn't open; I kept getting error messages, even after troubleshooting compatibility. So I ditched '13 and skipped to '15 and it worked but very slowly. I would try right clicking the shortcut to the program > "Properties" > "Compatibility" tab > "Run compatibility troubleshooter" button then follow the dialog boxes. That should hopefully work.