Outlook 2010 under win 7 with some hosted exchange from some obscure supplier. (dont know for sure what this is exactly, this is for a friend far away, not very knowledgeable) Just letting outlook standing idle, and after a short time: "Unhandled exception has occured in a component in your application. If you click continue . The application will ignore this error and attept to continue" "Details" seem to indicate problem with .net framework 4.6.1. Have uninstalled 4.6.1, and installed 4.5.2. But then send/receive results in sync error of some sort. Reinstall 4.6.1, and we are back with "unhandled exception......." from time to time. Seems this install must have 4.6.1, 4.5.2 no good with exchange. Any hint for solving this problem ?