I can't speak for N, but I haven't found anything that doesn't run on LTSB. I imagine N might affect things that need media playback capabilities (I think you can also install a media pack to fix those), but you're better off waiting for someone who knows more about that to reply
You can run any game on any edition, be it N or non-N. If you don't need windows media stuff in general, then you're perfectly fine with windows N edition, you won't run into any problems.
Some games (very few) for some reason requires Media Features. If you're also using software like Nvidia Shadowplay, not sure what you need for AMD's Relive. you also need Media Features. Simple fix by installing Media Pack from MS.
Only limitation you really will notice it that you need the windows media pack because e.g. if you want to mount your e.g. Android it requires this, otherwise it can't see/scan your media/sdcard.
I haven't come across any games that don't work on LTSB either. Grand Theft Auto 5 was one particular game which required the Media Features Pack to be installed with N editions. Starcraft, Diablo II are working. Warcraft 3 has broken videos atm (codec problem on x64 - due to be fixed) GoG have got a massive selection of classic games which are mostly all working; Thief; even old Dark Forces 2 Jedi Knight. There's open source versions of Red Alert - openRA - and other similar projects like openXCOM. Pretty good for the most part. There's the usual problem of some older early DirectX games no longer working/crashing/glitching on Windows 10 - usually DirectDraw is to blame. Even GoG can't get some of those working perfectly =\ Getting more familiar with Linux is one of my goals.
The N version isn't developed as a feature but MSFT got forced to create them by the EU because they didn't want MSFT to include mediaplayer and other media features.
No SDcard works fine, but the Android devide (internal memory card) will not visible since it requires the media pack.
I don't get it. Running Win10EnterpriseLTSB2016 here with no media pack. In the interest of science, plugged my Galaxy s4 into my E5430, it loaded some drivers explorer showed the phone and it's sd card and I viewed some pictures on the card with iview, my default viewer I don't see any limitation ...T