as long as your machine does not use DCH-based drivers from Intel/nVidia/AMD/Realtek, you could remove MS store I did not really need store for the older LTSB 2016 version but I install it for LTSC 2019 RS5 because I use some DCH-based drivers that require some UWP apps from MS store
My AMD software thingy still gets installed in "C:\Program Files\WindowsApps" even without store I don't know if they are DCH-based drivers Spoiler