The only game I've tried on Windows 8 that won't work is Act of War: High Treason :/ however, getting it to work on Windows 7 was also extremely difficult so not sure if that counts.
Planet Side 2 (Steam) maybe non steam too Problem: Fails on load Fix: place Dinput8.dll in the base PS2 folder, OR disconnect all USB devices load game then plug them back in Problem: UI strings are all wrong Fix: change regional settings to another language, start the game, quit, Change back to english.