Guess why I always get upset when I hear people saying IVM does not work / cannot work against SARS-COV-2 I knew this already since last fall 2020 And I know and understand all details... It is unbelievable how much destructive power and irrationality is used to try to 'kill' IVM. Like:" What? You are taking a horse dewormer to fight COVID? Are you nuts???". To 'be' reasonable one has to take experimental gene based vaccines which are considered to be safe and not that dangerous as 'horse' medicine. THIS is sold as rationality and 'truth'!!! OK, the 5 MOAs (to have them mechanisms of action here at MDL as well). Simple terms and one source at least. Added more sources 11/11/2021 1 At infection SARS-COV-2 binds with its spike to the human ACE2 receptor. IVM binds to the spike and ACE2. By that it sits in between and can inhibit the infection. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652439/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7996102/ 2 Disrupts RdRp an enzyme needed for viral RNA replication. As being said earlier. https://www.frontiersin.org/articles/10.3389/fmicb.2020.592908/full https://www.researchsquare.com/article/rs-73308/v1 3 Disrupts another enzyme which is called 3-chymotrypsin like protease (3CLPro). Is pivotal for viral replication. There are certain enzymes which are responsible to translate certain areas of viral RNA Info: https://www.nature.com/articles/s42003-020-01577-x https://pubs.rsc.org/en/content/articlehtml/2021/cp/d1cp02967c https://pubs.acs.org/doi/abs/10.1021/acsptsci.0c00108# 4 Disrupts viral cargo to the cell nucleus. The transporter are Importin alpha/beta. Usually when a human cell recognizes a stressor it creates substances (for instance IFN-alpha and Tumor necrosis factor TNF) in order to increase defenses for the nucleus and markers to the neighbor cells to alarm them as well. SARS-CoV-2 now uses these transporters Importin alpha/beta to send a message to the nucleus making the defenses staying low and preventing the warning to the neighbor cells. IVM blocks the message from being attached to the transporters Importin alpha/beta. So there is no delivery to the nucleus.. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327999/ This is also mentioned at the article posted by Pallandin above. It's been found at HIV and dengue before, but since SARS-COV-2 uses these transporters as well, it's an MOA against it, too. 5 And finally it disrupts NF-κB pathway. This means is anti-inflammatory and reduces the risk for a cytokine storm to occur. Why it matters: https://www.frontiersin.org/articles/10.3389/fimmu.2020.598444/full And why it can: https://pubmed.ncbi.nlm.nih.gov/19453757/ General docking study: https://www.frontiersin.org/articles/10.3389/fmicb.2020.592908/full The 'game changer' for 1.2 Billion Molnupiravir from Merck has only one similar MOA to 2. A joke.
Interesting discussion regarding having to show you Covid-19 Vaccine certificate to enter various establishments. https://market-ticker.org/akcs-www?post=243802 .
Meanwhile in bikini bottom, spongebob and friends are overdosing. https://news.yahoo.com/ivermectin-calls-poison-control-centers-004841746.html @Yen i was reading this article and it made this statement ... ... Is that true? If it is, what's the difference, just dosage or different structure?
The answer is...Kinda. bottom line is that 1% Ivermectin for a horse is the same as 1% solution for humans. There is however paste, and some other external animal products that you might want to stay away from. They state the obvious that the medication is for a horse and that dosage will be different that for a human. Duh! Now what they don't say is what's the correct dosage for humans. They only say that you can overdose. It's like saying taking too much Vitamin D will kill you, and if you took 200 2,000mg pills it would probably kill you. But whenever they mention dosage of Vitamin D, they always mention what the average dosage should be, or at least a range. Notice when they try to say Ivermectin is bad for you they always qualify it with plenty of, "could cause" and then a list of things that could be caused by taking Ivermectin. Yet they never say, "will cause", only "could cause" to gen up fear. Attached is something Yen came up with when I was first asking what the correct dosage should be and how to convert pill dosage, measured in grams to be converted to liquid measured in CC's. Attached is the edited version of what he told me to do, along with a simple chart the MSM will never show you that shows the correct dosage of the liquid 1% solution in CC's dosage in relation to weight. If the MSM was so concerned with you health they would publish this simple chart to prevent the overdoses they are so worried about. The MSM would never link to this explanation of how to go about taking Ivermectin safely: https://www.barnhardt.biz/ivermectin/ .
https://www.medrxiv.org/content/10.1101/2021.08.19.21262139v1.full A California study showed that vaccinated people are more susceptible to infections caused by the COVID variant than unvaccinated people.
It's the (galenic) formulation that is different. The science behind it is galenics. 1) There is the active drug IVM. There is no other active drug inside. This means the structural formula is exactly the same. The pure drug has to follow specifications, especially concerning impurities. There is for instance the USP standard (US Pharmacopoeia). It could be (if at all) that IVM for animal administration is allowed to have a bit more of impurities. But this usually does not apply to the formulation: injection solution. Here's the highest quality used. 2) The pharmaceutical additives. Depending on which galenic formulation you have several pharmaceutical additives. Those have a purpose as well, a galenic purpose. For instance to press the drug into a pill you cannot just press the drug alone. It would be either an inappropriate amount (either too low or too high) or a bad physical behavior (the pressed stuff just brittles again)... At solutions just as injection solutions you have to specify the solvent. If it is not saline, you have to check what it is and how it's to human body. I did that (propylene glycol, glycerol formal.) Both substances are harmless to human body, although this combination is mainly used at veterinary meds. The issue with veterinary IVM is the correct dose. A horse has another body weight than a human. I also posted a disclaimer because I know that when I 'advocate' IVM some might use the veterinary stuff and might calculate the wrong amount (over-dosage). Actually there is no issue taking veterinary products. Thanks for this. But what is more concerning to me is that bit: "In summary, our results reveal that selection pressure in a highly vaccinated community (>71% fully vaccinated as of early August 2021) favors more infectious, antibody-resistant VOCs such as the gamma12,32 and delta12,13,21,25 variants, and that high-titer symptomatic post-vaccination infections may be a contributor to viral spread. Concerns have also been raised regarding waning immunity resulting in decreased effectiveness of the vaccine in preventing symptomatic infection over time33. Combined with other potential factors such as relaxation of COVID-19 restrictions and complacency due to “pandemic fatigue”, these data may explain the recent steep rise in COVID-19 cases in San Francisco County (Figure 1)34 and nationwide18 in July-August 2021. Targeted booster vaccinations for vulnerable populations35, potentially guided by monitoring of immune correlates of vaccine efficacy30, will likely be needed in the near future to control viral spread in the community." I always said a mass vaccination approach makes no sense. (Can turn out as a backfire). Especially to vaccinate 'into' an ongoing pandemic can tun out as a boomerang... What many people do not understand. In vaccinated people there is a selection pressure, because the vaccines make a certain static antigen. It is still the Wuhan S protein. And we know vaccinated people do infect others. They are leaky (non-sterilizing) vaccines! The more the virus mutates there, the farther away from the vaccines the mutations will be. And by that the chance to escape, because the efficacy diminishes by the amount of variation. The unvaxxed don't have a pre-immunity based on a particular strain / Wuhan and so they have no selection to a particular variant. Their 'naive' immune system kills any strain with the same affinity. This posted article goes into that direction. The first time. If it turns out that way, we will experience that the mass vaccination turns things even worse...means the VOC's are favored in the vaxxed and by that keep the pandemic moving on....a sort of cat and mouse game....(where you have to adjust the vaccines again and again without really getting long lasting natural immunity). It will result in a high infection plateau (it never gets really down).....it stays there with minor changes....Israel and nations with high vaccination rates should be first showing that... Guess why we never vaccinate into a flu season and do the jabs before an upcoming season to have a 'wave-breaker' so a flu epidemic actually never can occur? Hmm..always willing to say....the basics of epidemiology cannot be bent.
I think it will end, and very soon, just as it ended before - with destruction. They will drop another 50 nuclear warheads of 150 megatons each and that will be the end of it. _______________ https://theexpose.uk/2021/09/12/three-studies-find-the-covid-19-vaccines-do-not-work/
Just look at this: https://www.reddit.com/r/KochWatch/...eal_globalists_are_the_kochs_and_the_mercers/ Especially: https://www.reddit.com/r/KochWatch/..._bannon_pledges_20k_shock_troops_as_he_rants/ And: https://www.reddit.com/r/KochWatch/comments/pzhm81/kochbacked_group_fuels_opposition_to_school_mask/
Post-vaccination nephrotic syndrome due to Minimal Change Disease I share the link to a case report that was published in the American Journal of Kidney Disease: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8028833/ . The article documents a case of a disease known as "Minimal Change Disease (NDE)", which is an affectation of the kidneys that can be severe and is the main cause of nephrosis (kidney damage) in children. The clinical report consists of the case of a 50-year-old healthy man (without comorbidities) who 10 days after receiving the SARS-CoV-2 vaccine experienced acute kidney damage and nephrotic syndrome. The clinical signs of him had started within four days of the first dose of the Pfizer vaccine, and included edema (accumulation of fluid) in the legs, hands, abdominal wall and penis. He had altered some blood and clinical parameters that were indicative of severe kidney damage. His kidney function continued to deteriorate and he had to be treated with corticosteroids and hospitalized for 10 days. The clinical picture has been described in other conditions, including the reception of some vaccines, such as Influenza. Although the authors acknowledge that the association between the reception of the SARS-CoV-2 vaccine and the occurrence of NDE kidney damage, they indicate that it is the first case and that they should wait for more reports to know the true incidence of this "possible adverse effect of the vaccine ". The interesting thing is that this study was published in April 2021, and since then more reports have indeed been reported, 14 in fact, and associated with the Pfizer, Astrazeneca, Johnson & Johnson and Moderna vaccines. I also share the links to these articles: https://pubmed.ncbi.nlm.nih.gov/34143368/ https://pubmed.ncbi.nlm.nih.gov/34119510/ https://pubmed.ncbi.nlm.nih.gov/34181144/ https://pubmed.ncbi.nlm.nih.gov/34000278/ https://pubmed.ncbi.nlm.nih.gov/34242687/ https://pubmed.ncbi.nlm.nih.gov/34119512/ https://pubmed.ncbi.nlm.nih.gov/34023417/ https://pubmed.ncbi.nlm.nih.gov/34048824/ https://pubmed.ncbi.nlm.nih.gov/33992727/ https://pubmed.ncbi.nlm.nih.gov/33839200/ https://pubmed.ncbi.nlm.nih.gov/34052236/ https://pubmed.ncbi.nlm.nih.gov/33964312/ https://pubmed.ncbi.nlm.nih.gov/34342187/ https://pubmed.ncbi.nlm.nih.gov/34337193/ Due to the seriousness that nephrotic syndrome and acute renal failure can have, it is important and necessary for doctors to be aware of these adverse effects in order to be able to recognize the symptoms in a timely manner in vaccinated patients, as well as to have more elements to recommend, based on the patient's medical history, the decision that is best for the integrity, safety and well-being of the patient as to whether or not to receive the vaccination. I hope you find this information useful and pass it on to your medical acquaintances as well as loved ones with kidney problems, who may be more susceptible to this adverse effect. I send you greetings, Karina AW https://t.me/akashacomunidad/603
This is great INTERNATIONAL COALITION FOR OPEN-SOURCE PHARMACOVIGILANCE (INT'L VAERS) JUST LAUNCHED https://odysee.com/@Welcometheeagle...vigilance-(Int--x27-l-VAERS)-just-launched!:4 https://www.bitchute.com/video/iGlNvbb0QJbc/
BBC is one of the initiators of "TRUSTED NEWS INITIATIVE TO COMBAT SPREAD OF HARMFUL VACCINE DISINFORMATION" https://www.ebu.ch/news/2020/12/tru...mbat-spread-of-harmful-vaccine-disinformation This 'initiative' obviously tries to censor anything that could be a competitor to the vaccines. The BBC article you have posted is a load of assumptions. There is no reference to the mentioned studies nor a proof that studies should have been manipulated. The psychology of the BBC and others to 'kill' IVM is to lie and to bend facts. In fact most IVM articles have been rejected because nobody wanted to have good results being published. I evaluated studies myself applying 'my professional skills' and I came to the conclusion that IVM works. This BBC article is no issue for me. I know that they are spreading lies. I also know lots of docs using IVM with success. And I am not alone with my assessment. How often one has to repeat lies until they become public truth? As being said....the MSM landscape is poisoned, you never will get there real info. Anything there is distorted. Journalism is within its greatest crisis of losing independence and proper art of journalism itself. And also they have 'scientists' on their side. Those being involved in big pharma and big money. This is actually 'the issue' I am worried about. There is a power behind that glorifies vaccines and diminishes any repurposed drug. (competitor)... Results that might harm the vaccines are suppressed..and also good results of alternatives are. Any previous SARS vaccine development has been halted due to ADE. But this time they simply skipped the tests before and they even DO NOT check virus levels (I mean real levels) and compare them to the unvaxxed. For the people (reader) it's hard to make a valid opinion. Finally all appears to be a mutual 'blaming' of each others to spread misinformation. But who's 'missing'...with intent? Paul Marik P. Kory Joseph Varon Hector Carvallo Eric Osgood Tess Lawrie Syed Haider and many more... All people with great reputation and loads of scientific publications in the past. Their expertise is based on profession and without conflicts of interest.
The media these days is always beholden to the people paying for their opinions to be aired. Same with politics, it's always two sides of the same coin. Very hard to find a truly neutral article on anything. Even the actual studies could be paid assessments.
Funny that such "obvious" benefits of IVM still have no "obvious" studies to prove it, though... And quite some time has passed...