Coronavirus | Discussion

The awareness to do something for what we call health is as old as humankind. (collect / use herbals...) and later 'nutrition'

So if we are now intellectually able to understand what's responsible for 'something' that might affect 'health' we can change our behavior...generally spoken.

The most natural consequence would be to avoid wintertime and to move to a place where there are no seasons...

 

"Snake venom" came up by this article, released by the University of Arizona:

"Like Venom Coursing Through the Body: Researchers Identify Mechanism Driving COVID-19 Mortality"
https://news.arizona.edu/story/veno...identify-mechanism-driving-covid-19-mortality

They decided to use a clickbait headline. The study to which they refer to is: https://www.jci.org/articles/view/149236
The substance which seemingly associates to snake venom is Group IIA secreted phospholipase A2
The research was done August 2021 already!

And then far later.... if a 'doctor' picks that up Dr. Bryan Ardis, saying such a crap, it could be true....and the conspiracy theory folks have another topic.
What is the 'weapon' against it?
Knowledge. Reading the original papers, getting familiar with the mechanisms.
Or reading closely for instance here:

Briefly:
What are phospholipases, or what is a phospholipase?
Anything that ends with -ase points to enzymes. Enzymes biochemically decompose / break other molecules by a selective and specific catalytic effect.
Protease decomposes proteins, Dnase decomposes DNA, Rnase decomposes RNA, phospholipase decomposes phospholipids.

What are phospholipids? They belong to the cell membrane lipids, are a component of it. They build double layers to separate what is in a human cell from what's outside.

SARS-COV-2 has an envelope (not all viruses have an envelope). When the virus captures a human cell and more viruses are made, the virus gets out of that infected cell. By that it takes a part of the human cell membrane and uses it as its own envelope. It is stolen so to say and not an own product of the virus.
So phospholipase can break cells and the envelope of SARS-COV-2. (or generally membranes of pathogens when they consist of phospholipids.)

The association to snake venom is because some snake venoms also contain Group IIA secreted phospholipase A2. The purpose is to break cells of the victim.

BUT the Group IIA secreted phospholipase A2 they are talking about is NOT from snake venom it IS self made (pancreas)!
It has a human biological function. And the amount of it in the blood is increased at those having severe covid. At acute (end) state it can blindly attack and destroy own cell membranes.

Whenever there is an infection and inflammation human body releases APPs (AcutePhaseProteins) and phospholipase belongs to them.

And additionally whenever we eat food it is made to decompose / break / digest cells of the food "meat=animal cells". It is also in our digestive system.

This is nothing new.
But what's usually missing is the fact that everybody who has got natural infection ALSO puts escape pressure on the virus! The immune system is NOT naive anymore and 'knows' the variant of the first infection perfectly.

So it is pushed to change there as well. Anyway once the virus has become that much contagious a coexistence without any significant mutation is possible. Is it the BA.2 variant already which will only come up with further sub variants? We will see.
When now administering a vaccine to a 'naive' individual that is updated to Omicron, yes, you put additional escape pressure on Omicron. So the original wuhan based vaccine has pushed escape pressure on the original variant.

What's far more sad at vaccines is the fact that you are doomed when having adverse events from it! Far worse than having long COVID which is now 'recognized' as such, at least more and more.
But adverse events of the vaccines are still not recognized as such!

"Covid-19: Is the US compensation scheme for vaccine injuries fit for purpose?"
https://www.bmj.com/content/377/bmj.o919

 

I always find it funny when you are talking in 3rd person.
But this time it's confusing.
Bat2 is your wife with the hep issue, right?

So are we talking about a probable reactivation due to vaccine? Or due to natural infection, or both?

Can you please tell me when exactly the hep issue has occurred? How many days after which shot?

A reactivation of dormant viruses is also a very individual thing.
It didn't happen to me so it cannot be....is no valid argument. This argument unfortunately does generally not apply much to COVID.

Anyway I am curious about those kids. At some hepatitis was that much severe that they needed a liver transplant!
They did not find any hep virus, though. No A to E. But Hepatitis which is actually liver inflammation can have other causes, too. Also other viruses, they mentioned an adenovirus.

IMHO those kids do not suffer from a reactivation. They rather suffer from a 'collateral damage' coming from measures against spreading of SARS-COV-2.
Those are young kids. Young kids have the innate immune system and are heavily training their adaptive immune system by getting exposed to many pathogens.
This is a very important process. Their immune system need a constant irritation by different pathogens, the mentioned training which is far more important at this age as when being adult.
They had to break for 2 years!!!. Wearing masks. So the immune activity declined. Defences declined.

And then reopening....a circulating virus and bam! No defences...I bet the immune training break will unveil far more issues in the future..up to getting more allergies when being older...

There even must have been co-infections at the very same time! Otherwise there would be no recombinations of variants.
What some people do confuse.
Nothing ever would prevent infection.
No vaccine does, no natural immunity does. A virus enters human body and infects some cells.
The immune system has some latency. It takes time until the enemy has been recognized as such.

Imagine there would be antibodies for every pathogen one has encountered already circulating in the fluids in a sufficient amount to capture any virus...that would be simply too much and not efficient at all. ABs would age without any purpose and making of them uses loads of energy...guess why we are mostly tired when fighting with an infection...
BTW: This is the reason why waning of ABs is a natural process. No pathogen anymore, no demand anymore.

BUT the immune system can have such perfect defences that the infected one cannot shed the virus nor getting sick by it.

To be immune means not to get sick.
'Natural immunity' at COVID to be expected means only getting mild symptoms or even becoming asymptomatic.
BTW I'll watch your video later. I suffer a bit from myopia. ...but as I am getting older presbyopia can take over...

 

Wasn't it in the news that SARS-COV-2 has become even less fatal by Omicron?

The case count should not matter if the percentage is obtained by enough statistical power N (to represent a cohort).
Anyway some thoughts which have an influence on that....
It's reasonable to assume that vulnerable people die first....and once they have died they are not a statistical part of the potential vulnerable group anymore...

The value you pointed out is actually not much useful since COVID has the attribute to have a very irregular distribution on age groups / obese BMI / diabetes...

What's the real 'meaning' of the 'difference' of 99.79% to 99.699% WHEN it drastically decreases as soon as one belongs to one of such group?

Yes, that affects actually 2 values together.
Case AND fatality.
PCR positive does not mean sick by COVID.


And at fatalities ..died being PCR positive does not mean died BY COVID....

 

Make your self comfortable at your favourite place (on the couch or wherever) in the living room and watch this:

"Pfizer can't hide this ANYMORE"



If you are a stock holder you are lucky if you have got adverse events from their vaccine you are not.
Another lesson about how capital works.