Coronavirus | Discussion

Wow....somebody who is almost conform to anything I have posted...

"The need for a vaccine is still very large, the data doesn't change that."
Yep it'll vanish as soon as reason returns. We maybe should move focus to treatment.
Vaccine is for special groups of people only...and it could be that COVID-19 naturally fades before we get one at all...

 

Actually yes.

Although this is very far fetched it could be clearly excluded if they'd practise proper GLP. And to GoodLaboratoryPractice belongs a proper validation of the tests and approval there where it is used.

 

"Exactly what the antibody drop means for immunity is still uncertain. There are other parts of the immune system, such as T-cells, which may also play a role, directly killing infected host cells and calling to other immune cells to help out."

Your source refers to specific antibodies of COVID-19. It only briefly mentions t-cells. (Hence my answer actually yes. The difference is that I think t-cells are most important.)

Actually all what's posted there about specific antibodies is conform to what I know. A vaccine will use the same defence approach!
And yes the source mentions we do not know how will be the initial antibody level compared to a natural level, if the plateau is still enough, if we need a boost...that the level at elderly people is declining more....that we have very very few reports of a second infection....

Natural herd immunity..your stimulus.
I clearly differentiated two instances of immune defence. All the more even that is crux of my arguing since it is missing frequently.
One seems to be long term (t-cells) and one seems to be short term (specific antibodies)
At a natural infection and undergoing COVID-19 / corona illness you 'train' t-cells additionally.

And the two sources I have posted (there are btw lots of more cross references there) found out that t cells of blood samples which were never exposed to COVID-19 do recognize the spike protein of SARSCoV-2 to a high amount ~80%.

Here my initial post about (where I was very upset and you thought the original Yen has disappeared).
I settled down in the meantime....but I stick to what I mean about herd immunity....a combination of cross-immunity and t-cell response...and to an unknown amount of antibodies..

I thought I had illustrated what I mean by natural herd immunity.
-We have already cross immunity.
-We gain immunity by infections of former corona viruses and SARSCoV-2 infections (by t-cells)
-To be immune means you do not get ill. (It does not mean you do not get infected).

The 'other instance' specific antibodies is still controversial. It looks like but maybe not a long time.

But it actually doesn't matter. It's the result = actual immunity to COVID-19 what counts.
Your source is right, but only goes into the specific antibodies....a part of defence.

My surprise at this article is that it's one of very few that even mentions the t-cells at all.

 

About an exciting subject of research.
"Cross-reactive memory T cells and herd immunity to SARS-CoV-2"
https://www.nature.com/articles/s41577-020-00460-4

 

Wanna learn how PCR at corona is working?
https://www.otago.ac.nz/biochemistry/research/otago736925.html

The brothers:

Code:

SARS-CoV     SARS
SARS-CoV-2   Covid-19
MERS-CoV     MERS
HCoV-OC43    Common cold
HCoV-HKU1    Common cold
HCoV-229E    Common cold
HCoV-NL63    Common cold

And understand pitfalls
https://onlinelibrary.wiley.com/doi/full/10.1111/tbed.13684

And understand that PCR kits depending of supplier can have false positive rates of almost 50%....especially at low prevalence samples (random testing)...

Current news: Error rate of 96% (58/60) !!!!
https://www.reuters.com/article/hea...produces-run-of-false-positives-idINL8N2HJ321

 

That's not the point.

I post that to inform. I post that because this is no proper testing. I post that because it is a hit in the face for everybody who is conform to GLP. (We btw have to be trained every year about.)
Each analytical process here in the pharma industry has to be validated according to GLP. And rightly so!

But this PCR test affects the entire humankind, legal actions, interventions, freedom.
And it is NOT conform to GLP!

50% it's like playing dice! 5-10% is still a mess.

I expect a lawsuit, actually!!! At least those affected from the Augsburg lab.
Are you actually aware on the scope of this?

You take water (actually an aqueous buffer solution) to 10 PCR testing and you get the result 5 out of 10 is 'suffering' from COVID-19!
Not to speak of the 'water' would contain another brother of SRASCoV-2 which would add another 7% of false result! (Source RKI Germany)....

Imagine this would happen to you. What's with your psyche then, your family life, your kids.
You would think you are going through this with all consequences, but actually there is nothing at all.