Hmm.... "The genetic structure of SARS‐CoV‐2 does not rule out a laboratory origin" https://onlinelibrary.wiley.com/doi/10.1002/bies.202000240 Some valid points.
See? This is what I've always thought. This plandemic suits perfectly to upcoming 2030 Agenda. Everything is planned and constructed, including the dang virus. Corona emergence has a perfect timing for that goal. Impossible to be a true natural emergence. This is fully artificial.
ARGHHH!!!! https://www.theguardian.com/world/2...pe-in-covid-treatments-fails-against-variants Exclusive: no leading contender is effective against all the South African, Brazilian and Kent variants
This belongs to the very basics of Biology and has to be expected. I don't know. To have hope on monoclonal antibodies at a RNA virus is evident that the one has absolutely no clue of the very basics of Biology. Heck, I haven't studied Biology but what I've got as a side knowledge is even sufficient not to fall for such illusions. The guardian article author is a bulls**tter. The Brazilian P1 variant is most 'advanced'. A virus has no consciousness, it's not even a living being. The RNA reproduction process is flawed by nature to get random mutations. Most of them are retarded. The rule for 'separation' is survival by the fittest. But the principle is: Let's create random changes and have a look which one survives most related to the host environment. When you get infected even your individual body alone creates lots of mutations. It's quite normal. But the chance that there is a new variant that attracts attention is relatively low. The solution is to design new monoclonal antibodies that are related to the changes at the target. The same applies to the vaccines. AFAIK Moderna is already creating a new mRNA that reflects the changes. You even could use different mRNAs for each variant in one shot. But....its not yet clear if the vaccination approach in general would be a solution to stop the pandemic!
Another thing that makes me upset about monoclonal antibodies. Bamlanivimab (LY-CoV555). Their study which led to approval was like... 3 groups of people (100 each). Each group has got an individual dose (3 doses). And there was the placebo group also 100 people. This means. The placebo / verum study consisted of only 200 people. (100 to 100 of one dose comparison). WoW. It's been significant enough to have got approval. AND even though it has to be expected that they lose effectivity at other variants. On the other hand there is ivermectin. -It's been used since ages and is safe -There are many many more significant studies with many many more people. -The MOA is well understood. -It works and it will work at all variants since it blocks a very generic transport. Anyway there is resistance and bad mouthing on ivermectin. I have to assume its due to lobbyism and politics. Ivermectin is cheap and 'old'. Bamlanivimab is new and expensive with a great margin. Current decisions and politics and measures have NOTHING to do with reasonable science. People are still dying because they do not get effective drugs in time! People are dying because of false decisions. I NEVER have seen such a mess since I live. Glad I could share some infos.
Hehehe... you can create a family tree. This is evolving. I post a snippet to get an impression. Here we speak of 17 amino acid changes, 3 deletions and one insertion altogether. (Compared to the most common ancestor). The 'concerning' mutations (all them affect the S-protein RBD). N501Y (found at the UK) E484K (found at the South Africa variant) K414N (found at the South Africa variant) All them 3 are found at the Brazilian P1 variant...and so on and so on...
Virus's evolve / mutate ......... but usualy within limits = It might get worse = More infectious and maybe more deadly ...... but ...... only up to a point .......... and then it either evolves to be less dangerous / infective ...... or we develop imunity . remembering that if the virus gets more deadly it kills the people it needs to spread itself and survive ? SO ...... either that is wrong ? ...... because this virus mutated from the original to the more dangerous british variant ........ wich then mutated to be worse that that = Its getting more dangerous and we have something to worry about ............ or ....... the asumption is right = IT = ther virus / consequences / death rate will soon level out and drop .
From the pure scientific view (mutations are used to fearmongering by common media). They mutate to a more contagious version and less deadly. If the host would die it could not spread anymore. Just like MERS.
So what we realy need is a virus that can survive on surfaces for a long time = it doesnt need a live carryer .
https://pace.coe.int/en/files/29004/html 7.3.1 ensure that citizens are informed that the vaccination is NOT mandatory and that no one is politically, socially, or otherwise pressured to get themselves vaccinated, if they do not wish to do so themselves; is this how they will do it? If the entrance to the metro is impossible without a Covid passport?
Why are people complaining about having to have a vacination ? In yurp we already have compulsary vacinations in schools for several diseases ......... Poliio ? Mumps ? Measels ? Diptheria ? Tetanus ? and ? ...... so whats the problem ?
The blue masks are tested ? ....... and allthough they're useless they got through the tests ? Two things the usefullness of masks depend on = The pore size of the pores in the mask ...... and ...... the fit of the mask . The newer PPF2 masks are better than the blue op masks because they fit better . The question isnt how big the pores are ...... the question is ........ are we breathing through the mask ...... or ...... are we breathing AROUND the mask . In the second case the mask is useless whatever the pore size is . The blue masks dont fit on the face properly ....... people breath around them and not through them ....... and thats why the better PPF2 masks were developed . WITH a mask that fits properly the pore size decides the preasure that we have to use to breath through it ....... and the size of the droplets that get through it . IF we breath around the mask the droplets dont get held back ....... so the mask is useless .
EU authority reports doubts about FFP2 masks in everyday life that makes little sense Most federal states decide against an FFP2 mask requirement in shops and in public transport. The EU health authority also sees no reason to recommend wearing these masks in everyday life. You would not protect against infection with the coronavirus much better than others. In the fight against the coronavirus, the EU health authority ECDC arouses doubts about the additional benefit of FFP2 masks in everyday life. "The expected added value of the universal use of FFP2 respirators in the community is very low," said the Stockholm-based authority at the request of the German press agency. The costs and possible disadvantages also speak against a recommendation to wear FFP2 masks instead of other masks in public. The particularly tight, but more expensive masks are designed to protect against pollutant particles such as dust or aerosols. They are now required in many places instead of normal everyday masks. In mid-January, Chancellor Angela Merkel and the Prime Minister agreed to demand FFP2 masks, surgical masks or mouth and nose covers of the KN95 / N95 standards in public transport and in shops. EU Health Commissioner Stella Kyriakides confirmed the assessment of the EU authority in Brussels. "The ECDC says the evidence is not strong enough at the moment for a need to recommend this in everyday life," Kyriakides said when asked. https://www.n-tv.de/wissen/FFP2-Masken-im-Alltag-nur-wenig-sinnvoll-article22336308.html
Streeck on the corona strategy "Advises against everyone useing FFP2 masks" FFP2 masks are considered the new standard in the fight against corona. The virologist Hendrik Streeck explains why he thinks little of the general obligation that has now been imposed and why Germany as a whole needs a Plan B. https://www.n-tv.de/mediathek/video...-jeder-FFP2-Masken-nutzt-article22320562.html
Comedians here in the UK were taking the piss out of Tesco's superstore, as they had a slogan "Every little helps", alluding to its slightly lower prices than other similar superstores... So, naturally, if you're gonna do that, they were gonna say this: "Every Lidl helps!" Tah-daaaahhhh!!!! There's saving tons of work and paper...
Or slightly less humorously... https://www.theguardian.com/world/2...tm_source=esp&utm_medium=Email&CMP=GTUK_email Covid coughing study suggests NHS staff at far greater risk than thought Exclusive: Health service urged to rethink safety for frontline staff and provide better PPE and ventilation A member of intensive care staff, is ‘fit-tested’ for an FFP3 mask. There are now demands for anyone caring for a Covid-19 patient to have one. Photograph: Jonny Weeks/The Guardian "The NHS has been urged to rethink safety for thousands of frontline staff after new research suggested that Covid patients’ coughing is putting them at far greater risk of catching the virus than previously thought. The study found that coughing generated at least 10 times more infectious “aerosol” particles than speaking or breathing – which could explain why so many NHS staff have fallen ill during the pandemic. The research has led to fresh demands that anyone caring for someone with Covid-19, or suspected Covid-19, should be provided with the most protective equipment – including FFP3 respirator masks – and that hospital ventilation should be improved. Health workers are up to four times more likely to contract coronavirus than the general population, with infection rates among those on general hospital wards approximately double those of intensive care unit (ICU) staff – who do have access to the most protective PPE." Oh and look at this... Covid-19 in the UK Mar Daily cases 19,202 -6,106 vs last week Daily deaths 1,322 Total deaths 109,335 Vaccination rollout Dec Daily vaccinations 374,756 +63,696 vs last week Total received first dose 15.0% Cases, deaths and first dose vaccination data as published 3 Feb 2021. Weekly change shows difference from 7 days ago. Data: data.gov.uk