Coronavirus | Discussion

Discussion in 'Serious Discussion' started by luzea, Feb 28, 2020.

  1. Mr.X

    Mr.X MDL Guru

    Jul 14, 2013
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  2. Mr.X

    Mr.X MDL Guru

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    11 States Sue U.S. Government Over COVID-19 Vaccine Mandate for Federal Contractors

    @COVID19Up: Eleven U.S. states with Republican governors sued the Biden administration on Friday (Oct. 29) seeking to block a COVID-19 vaccine mandate for federal contractors, arguing it is unconstitutional and violates federal procurement law.

    A joint lawsuit was filed in the U.S. District Court for the Eastern District Of Missouri by 10 states, Arkansas, Alaska, Missouri, Iowa, Montana, Nebraska, New Hampshire, North Dakota, South Dakota and Wyoming. Texas filed a separate suit on the same issue, and Florida filed one on Thursday.

    The lawsuits described the mandate as "sweeping in its scope" and "unconstitutional and unlawful," citing a constitutional amendment on state powers and federal laws on government procurement.

    The mandate "is an abuse of power and we won't stand for it," Iowa Governor Kim Reynolds said.

    "It will only worsen the workforce shortage and supply chain issues that hinder our economic recovery and it furthers the unprecedented government intrusion into our lives," Reynolds added.

    https://t.me/COVID19Up/11379
     
  3. gorski

    gorski MDL Guru

    Oct 21, 2009
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    Heh, as if we don't know it was rushed...

    What was the alternative, btw?!?

    As in rational alternative?!?

    At the time, not now!
     
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  4. Yen

    Yen Admin
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    "Vitamin D Deficiency Is Associated With Higher Hospitalization Risk From COVID-19: A Retrospective Case-control Study "
    https://pubmed.ncbi.nlm.nih.gov/34139758/
     
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  5. MrG

    MrG MDL Expert

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    Indian Media Criticizes Pfizer After Ivermectin Success
    A media company in India are ramping up criticism of COIVD-19 vaccine suppliers following the nation’s success at treating the virus with Ivermectin. In a recent report, Indian television channel WION claimed Pfizer is maximizing revenues by selling COVID-19 vaccines to developing nations on often predatory terms.

    >snip<

    The channel cited a separate report by Public Citizen that detailed Pfizer’s distribution agreements in emerging markets. WION found those contracts give up power to some government authority to Pfizer.

    “Practically anything that a sovereign government owns — foreign bank accounts, foreign investments, commercial property, state-run airlines, even oil companies — Pfizer can takeover any or all of these from a government. Basically everything happens in Pfizer terms once a country decides to buy its vaccine.”

    — Palki Sharma, foreign affairs reporter – WION

    more at
    https://www.oann.com/indian-media-criticizes-pfizer-after-ivermectin-success/

     
  6. Mr.X

    Mr.X MDL Guru

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    #3446 Mr.X, Nov 3, 2021
    Last edited: Nov 3, 2021
    Techno-fascist Corporatocracy at its best.
    So now you all sheeple are starting to see the "real" reality, that is, a fabricated pandemic to give the final thrust to the abyss
    :tooth:
     
  7. Yen

    Yen Admin
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    #3447 Yen, Nov 3, 2021
    Last edited: Nov 3, 2021
    I know that video already "Gravitas: Revealed: How Pfizer blackmails countries for shots", also their mentioned former report.

    I have given it up to 'show' how Pfizer really is. As they closed their labs here they kicked off their trainees. We took 2 of them to give them the opportunity to finalize their training.....
    They ever had been reckless....and their Viagra was purely based on coincidence.

    Also the mRNA vaccine comes actually from BioNtech....and they (BioNTech) have copied ermm acquired patents from somewhere..the history of synthetic mRNA is also full of ego fights...the CEO couple of BioNTech did nothing much on their own though, but got honored for the vaccine and ehh....have heard he (CEO of BioNTech) is not even vaccinated with their own vaccine yet.

    In an interview he clearly said that he is waiting until the vaccine is updated. Since this didn't happen yet I conclude he is still not vaccinated.
    He knows why for sure!
     
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  8. Yen

    Yen Admin
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    #3449 Yen, Nov 3, 2021
    Last edited: Nov 3, 2021
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  9. gorski

    gorski MDL Guru

    Oct 21, 2009
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    Oh, dear - everything except the issues at hand...

    Well, it seems one can put this into a UK hand now: https://www.theguardian.com/world/2...al-antiviral-pill-molnupiravir-to-treat-covid

    UK first to approve oral antiviral molnupiravir to treat Covid

    Pill can be taken twice daily at home and priority will be given to elderly patients and those with health vulnerabilities
    [​IMG]
    Sajid Javid said the MHRA’s decision to approve molnupiravir marked a “historic day” for the UK.
    The UK medicines regulator has become the first in the world to approve an oral antiviral pill for Covid in a move that paves the way for tens of thousands of vulnerable patients to receive the treatment from this winter.

    Nearly half a million doses of molnupiravir, a pill that can be taken twice daily at home, are due for delivery from mid-November and will be given as a priority to elderly Covid patients and those with particular vulnerabilities, such as weakened immune systems.

    Prof Peter Horby, the co-leader of the groundbreaking Recovery trial of Covid treatments at the University of Oxford, said the decision by the Medicines and Healthcare products Regulatory Agency (MHRA) was very welcome and amounted to a watershed moment in tackling the pandemic.

    The MHRA said on Thursday that the drug developed by Ridgeback Biotherapeutics and Merck Sharp and Dohme (MSD), was safe and effective at reducing the risk of hospitalisation and death in people with mild to moderate Covid who are at increased risk of developing severe disease.
    England Covid infection rates doubled in over-65s between September and October
    The health secretary, Sajid Javid, said the decision marked a “historic day”, adding “the UK is now the first country in the world to approve an antiviral that can be taken at home for Covid-19. This will be a gamechanger for the most vulnerable and the immunosuppressed, who will soon be able to receive the groundbreaking treatment.”

    No 10 announced a deal last month to buy 480,000 doses of molnupiravir, also known as Lagevrio, after a clinical trial in the US showed a five-day course of the pills halved the risk of hospitalisation or death for at-risk patients. The first delivery is expected no earlier than mid-November.

    Molnupiravir interferes with the virus’s ability to replicate, meaning it is less able to multiply and reach high enough levels in the respiratory system to cause severe disease. Because the drug is most effective when given in the early stages of infection, the MHRA recommends it is used as soon as possible after a positive test for Covid and within five days of symptoms appearing.

    The drug is approved for people with mild to moderate Covid and at least one risk factor for developing severe illness, such as obesity, diabetes mellitus, heart disease, or being older than 60.

    “Following a rigorous review of the data by our expert scientists and clinicians, we are satisfied that Lagevrio [molnupiravir] is safe and effective for those at risk of developing severe Covid-19 disease and have granted its approval,” said Dr June Raine, the MHRA chief executive.

    “Lagevrio is another therapeutic to add to our armoury against Covid-19. It is also the world’s first approved antiviral for this disease that can be taken by mouth rather than administered intravenously. This is important because it means it can be administered outside of a hospital setting, before Covid-19 has progressed to a severe stage.”

    Horby said: ‘‘The approval of an oral antiviral for Covid-19 is a major scientific achievement and, to me, feels like a bit of a watershed. The MHRA are to be commended for, once again, moving very quickly to ensure the UK population gets access to drugs with proven benefit.

    “We do, however, have some more work to do, such as ensuring access and affordability, avoiding drug resistance, and seeing if this drug can benefit other patient groups such as those hospitalised with Covid-19.”
     
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  10. gorski

    gorski MDL Guru

    Oct 21, 2009
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    Also: https://www.theguardian.com/society...drug-trial-tackle-fatigue-long-covid-patients

    UK launches trial of drug to tackle fatigue in long Covid patients
    AXA1125 targets cell power plants that may be dysfunctional in long Covid patients with severe fatigue

    Linda Geddes Science correspondent

    The first trial of a drug to target the fatigue and muscle weakness experienced by more than half of people with long Covid has been launched in the UK. It is also the first drug trial in long Covid patients who were not hospitalised during their initial infection.

    The drug, called AXA1125, targets cellular power plants called mitochondria, which it is thought could be dysfunctional in the subset of long Covid patients with severe fatigue. If successful, it could pave the way for similar trials in patients with other forms of post-viral fatigue, including myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

    Mitochondria help to regulate various cellular processes, and play a crucial role in transforming the chemical energy from our diets into adenosine triphosphate (ATP) – the energy currency that cells depend on to drive essential reactions.

    Supplies of ATP are quickly exhausted, so cells must constantly regenerate it. This can be done through a process called glycolysis, which produces lactic acid as a byproduct. But ATP is produced more efficiently through oxidative phosphorylation, which involves the mitochondria.
    Mounting evidence suggests Sars-CoV-2 can hijack cells’ mitochondria, boosting viral replication but disrupting ATP production in the process.

    “In essence, it’s a fuel switch. The virus invades the mitochondria and seeks to move it towards glycolysis to produce more viral particles, but it leaves the cell damaged,” said Bill Hinshaw, the president and chief executive of Axcella, which developed the new drug.

    An estimated 56% of long Covid patients suffer from fatigue and many also struggle to exercise. “We originally thought that these symptoms were related to organ inflammation,” said Dr Betty Raman at the University of Oxford, who is researching the impact of Covid-19 on organ health. “But six months down the track, we found that although the heart and lungs were seen to be recovering, these people were still unable to exercise.”

    Further investigation revealed that they were accumulating lactic acid in their muscles at a faster rate than healthy individuals – a possible sign of mitochondrial dysfunction. “In a normal, healthy person, the mitochondria will be very active in replenishing the ATP to sustain energy,” Raman said.

    AXA1125 is designed to normalise mitochondrial metabolism in diseases where it may be out of balance. So far it has been tested in patients with non-alcoholic fatty liver disease, with some promising results.

    Raman is launching a study in 40 patients with severe post-Covid fatigue to see if it can improve their exercise tolerance, reduce fatigue and improve mitochondrial metabolism in their muscle tissue – something that can be visualised using imaging techniques. Half will be given AXA1125 for 28 days, and the other half a placebo drug. Results are expected by mid-2022.

    “I don’t think this one drug will be the solution to everything because long Covid is such a complex disease, but [if it works] it will benefit a significant proportion of patients,” Raman said.

    Covid-19 in the UK
    Mar
    Daily cases
    41,299
    -2,642 vs last week [​IMG]
    Daily deaths
    217
    Total deaths
    141,181

    Vaccination rollout
    Dec
    Received 1st dose
    74.6%
    Received 2nd dose
    68.2%
    Received 3rd dose
    12.9%
     
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  11. Yen

    Yen Admin
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    Unbelievable!

    At least now we have sufficient preconditions for a repetition of a Contergan scandal.
    The drug is unsafe and only moderately effective.
    Compare those posts:
    https://forums.mydigitallife.net/threads/coronavirus-discussion.81224/page-170#post-1698223
    https://forums.mydigitallife.net/threads/coronavirus-discussion.81224/page-170#post-1698413

    or news like: https://www.reuters.com/business/he...-trial-moderate-covid-19-patients-2021-10-08/

    Look,

    this drug acts like fake genetic raw material which is used by mRNA to translate to proteins. What if it is not restricted to viral mRNA alone?!?

    TBH this is far more unsafe than all the genetic vaccines together!
     
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  12. Mr.X

    Mr.X MDL Guru

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    We know we know but gorski is an 3$5&@@
    Fun fact: he also knows :D
     
  13. Mr.X

    Mr.X MDL Guru

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    https://odysee.com/Vaccinated-vs-unvaccinated,-the-numbers:caae946e419bcd3434d2347c522f829d1bb9cd9d

    This video was produced based on official technical reports from Public Health England (the UK Health Ministry). I do not know who was the author of the video, but it presents accurate information, which you can verify yourself in the weekly technical reports (https://www.gov.uk/government/publications/covid-19-vaccine-weekly-surveillance-reports) . I thank the Task Force for their work in subtitling the material. The video shows compelling evidence that the incidence of COVID is higher in the fully vaccinated than in the unvaccinated. This is not resolved with more reinforcements; it is a direct result of the action of these vaccines.

    https://t.me/akashacomunidad/701
     
  14. Yen

    Yen Admin
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    It's also starting to unveil some abysses at the vaccines as well.....published at the famous BMJ

    "Covid-19: Researcher blows the whistle on data integrity issues in Pfizer’s vaccine trial".

    https://www.bmj.com/content/375/bmj.n2635

    No wonder that's always happening when capital outweighs reason.
     
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  15. Mr.X

    Mr.X MDL Guru

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    #3456 Mr.X, Nov 4, 2021
    Last edited: Nov 4, 2021
    The importance of integrity and impeccability in Science

    Someone once told me "the urgent many times does not leave time for the important." Throughout the profession that I chose and that I love to do, I have been in emergency situations, where you have to put aside some important things. Without going any further, last year, in the middle of a field expedition, more than 10 hours away from receiving any type of medical aid, one of the members of my expedition was bitten by an adult sea lion and the wound was serious enough to merit putting aside any matter related to the expedition and the research project to attend to the emergency and save his arm (and possibly his life). In addition to my scientific academic training, I am a Paramedic and I am trained in Expeditions Medicine, so it was possible to attend and resolve the emergency. My team member - and dear friend - healed very well (now he has one more adventure to tell), and the expedition continued, modifying some of the goals a bit.

    Why am I telling you all this? Because although it is understood that there are circumstances where it is necessary to focus on the urgent to the detriment of the important, in scientific research this should never happen. Something important - indispensable, central, essential - of science is integrity. This, along with impeccability, is a pillar that allows scientific work to generate knowledge that helps us understand the world, life, and possibly helps us use that knowledge to apply it to problem solving.

    Unfortunately, Science is done by humans, and humans are not necessarily upright and flawless individuals. Lack of ethics in Science is, unfortunately, a frequent occurrence.
    When he taught the subject of Communication of Science at the University, a complete subject was assigned to aspects of ethics in science. He taught students various and diverse examples of lack of scientific integrity, ranging from plagiarism of paragraphs to “spooning” of data, from photographic alteration of images to the complete invention of experimental results. If you are curious about it, you can see https://www.paho.org/hq/dmdocuments...tigacion-internacional-salud-Book-Spanish.pdf.

    My Professor of Veterinary Philosophy used to say “corruption is like pregnancy: you cannot be half pregnant; either you are corrupt, or you are not ”. His phrase struck me, because we tend to qualify and think that if someone plagiarizes a paragraph to do a task, that is not the same as inventing results in an experiment to receive financing (or accepting millions of euros, dollars or pesos to sign an authorization while look the other way). But in essence, it is the same: corruption, lack of integrity; And when it occurs in science, the effects of this approach can be devastating.

    The medical journal British Medical Journal published on November 2 (doi: https://doi.org/10.1136/bmj.n2635) a journalistic-scientific note on the “bad practice” of studies on the vaccine against SARS-CoV- 2 from Pfizer / BioNTech. According to research by author Paul D. Thacker, their speed in getting the vaccine cleared by the FDA affected data integrity and patient safety. Brook Jackson, who was Regional Director of a research organization "Ventavia Research Group" who conducted clinical trials of the Pfizer / BioNTech vaccine indicated that the company falsified data, removed the "blind" status of patients, used people not trained to carry out the vaccination, she avoided monitoring adverse effects in phase III and that when - due to these problems - the Director notified the FDA in September 2020 about these problems, Ventavia fired her from her job. What was said by Brook Jackson has written, recorded, videotaped and postal documented evidence.

    Since this report to the FDA, Pfizer hired Ventavia again to carry out four more clinical trials with its vaccine (in children and young people, pregnant women, boosters and a vaccine against respiratory syncytial virus, codes: NCT04816643, NCT04754594, NCT04955626, NCT05035212).

    The information gathered by the journalistic investigator should not be underestimated or nuanced. Think for a moment what it entails. Hundreds of millions of doses of the Pfizer vaccine have been applied to people in various countries around the world. The decision to authorize the application of this vaccine was derived from these studies. Studies that demonstrate a lack of integrity and impeccability. No epidemiological emergency justifies the lack of ethics in science. None! The consequences of these actions are already beginning to be seen. Without going any further, he sees the "need" to apply reinforcements because the vaccines are not protecting the vaccinated. We can explore the consequences in more detail. In fact, we have done it in several previous posts and we will continue to do so, but it mattered a lot to me that the members of Akasha Comunidad knew that these events occurred and do occur. It is not about being 'anti' or 'pro' vaccine. It is about being ethical and having integrity to accept when the facts do not suit what we would like to see, even if it hurts, even if it means economic loss; And it's about having enough common sense to make informed decisions. This that I present to you is part of the necessary information to consider if we want to receive said inoculation or not, if we want to give it to our children or not.

    I hope this information is useful to you and I send you my regards, Karina AW

    https://t.me/akashacomunidad/702
    https://t.me/akashacomunidad/703
     
  16. gorski

    gorski MDL Guru

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    Oh, genius, how can you possibly conclude from my factually pasted post - that I am all for it and uncritically so?!?

    I'll tell you how - 'cause you are a stoopid git with no minimal shame!!!
     
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  17. Palladin

    Palladin MDL Senior Member

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    I have followed this guy for a very long time, and he comes up with some thought provoking posts. This is the latest one regarding Covid-19 and basically this post says that the Covid-19 vaccines cause diabetes.
    https://market-ticker.org/akcs-www?post=244131

    It's a very complete discussion. Here's the link to the original post where he gets his info from:
    https://www.nature.com/articles/s41421-021-00329-3.pdf

    The first thing I noticed was that it was published in Nature Magazine, and the second was that there were only 11, count 'em eleven people involved in the study. Not near enough people to draw any meaningful conclusions. It might be 100% accurate with 11 people, but with 10,000 people the results might not be the same.

    The original document is 15 pages long, and is way above my pay grade to fully understand what they are talking about. Hopefully Yen can decipher the technical jargon and say yea or nae to the conclusions that were drawn.

    .
     
  18. moon510

    moon510 MDL Junior Member

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  19. Yen

    Yen Admin
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    #3460 Yen, Nov 5, 2021
    Last edited: Nov 5, 2021
    First maybe some basics of statistics. To look at trials people should at least know a little about.
    Sample size n
    Power
    Significance / p value
    zero hypothesis H0 and
    alternative hypothesis H1

    H0 is usually like: "There is no difference between vaccinated arm and placebo arm"
    H1: "There is a difference (in a particular matter for instance diabetes)."

    Power: The probability that a test correctly rejects a false zero hypothesis.

    Usually a study is planned in advance that way that the sample size is sufficient to get enough power.

    There are typically 2 kinds of errors:
    Type I error: The study shows a difference of 2 groups although there is NO difference in reality.

    Type II error: The study shows NO difference between 2 groups, but in reality there is a difference.

    In other words: Enough power means to avoid both errors type I and II or at least to keep them low.

    A sample size of 11 can be sufficient if you get low p values.

    We usually have the limit of p<=0.05 to say this has statistical significance.
    This means there is <=5% probability that the zero hypothesis is still right. In other words there is 95% probability that the alternative hypothesis is right.

    Or more simple: A p value of 0.05 means there is 5% probability that the results are random. Random means no difference between 2 groups = favors still the zero hypothesis

    Another value that is frequently found in study results is the confidence interval (CI), for instance the 95% CI.
    Also to consider that statistical significance and clinical relevance are different things.

    OK, now to the study.
    I don't know why diabetes should be a significant matter of this article.
    It's about a vaccine that uses complete inactivated virus.
    And it is clear that vaccination is an impact on human body and a burden.
    Goal is to mimic a natural infection without to have the issues coming with viral replication.

    It's quite normal that values get temporarily out of balance. And it's normal to advise that vaccination should only be done when there is no ongoing other infection.
    It's also normal that there is no immune response without Inflammatory related issues.

    The study figured out that it "....also influenced various health indicators including those related to diabetes, renal dysfunction, cholesterol metabolism, coagulation problems,.."

    I agree with that we do not really know much about what the vaccines are really doing and far more studies have to be made.

    "....our study recommends additional caution when vaccinating people with pre-existing clinical conditions, including diabetes, electrolyte imbalances, renal dysfunction, and coagulation disorders."

    There is no word of causing an illness such as diabetes. (Elevated markers belonging to a certain illness and illness itself are completely different matters).
    I also found no info there where they said the corresponding markers stay permanently...

    To say "COVID Vaccines cause diabetes" does generalize the vaccine types and is without evidence either way.

    To include the pre-existing clinical conditions of a person is part of proper risk benefit analyses.

    And if diabetes is an issue or not is strongly dependent on the fact whether the diabetes is controlled or not!!!

    Diabetes which is controlled is actually no big deal.
     
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