Coronavirus | Discussion

Discussion in 'Serious Discussion' started by Deleted member 1254778, Feb 28, 2020.

  1. Mr.X

    Mr.X MDL Guru

    Jul 14, 2013
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    No it didn't, it opens a new tab with just gibberish. I had to right click on the link and 'Save as'. Just reporting.
    Thanks a lot btw.
     
  2. Palladin

    Palladin MDL Senior Member

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    I'll look into it to see what's going on.
    Thanks for letting me know there was a problem.

    .
     
  3. Yen

    Yen Admin (retired)
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    Wow.....

    new findings about the behaviour of SARS-COV-2.....(I thought 'they' already had checked that---but it's a new finding!!!!)
    The virus could act like a bacteriophage!
    Bacteriophages are viruses which infect bacteria.

    An interest of this research was: Can there be another host except mammalian eukaryotic cells, which are also 'our' = human cells?
    Yes!
    They infect also bacteria which are living in our gut!
    It seems when bacteria there encounter the virus and they release toxins / proteases onto the virus, the viruses' surface gets modified...and THEN they can enter the bacteria! No other HCOV can!
    This changes a lot and adds many new insights / approaches.

    For instance it can explain why:
    There are GIT issues and imbalances in the microbiome. (Some bacteria die, others increase= change of balance there).
    Why the virus can stay 'in us' even longer.
    Why antibiotics which never can kill viruses could help / could be of use....

    This finding will induce new thinking...and changes the value of:
    Epidemiology (how they could spread)
    Therapy (how to treat gut issues)
    and even vaccinology....(develop oral vaccines with attenuated virus that can infect those bacteria)


    Vaccines | Free Full-Text | Could SARS-CoV-2 Have Bacteriophage Behavior or Induce the Activity of Other Bacteriophages? | HTML (mdpi.com)
     
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  4. Yen

    Yen Admin (retired)
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    I have gone through it completely.
    I am still baffled why it hasn't been researched about before.

    What I am thinking about right now....

    -role of faecal-oral route? An unknown but significant amount of transmission by it?
    -role of bacteria in creating mutations?
    -role of infected bacteria at long COVID

    And something I do not get:
    The sizes do not match.
    How can be a whole virus inside of a bacterium if the virus is supposed to be 100 nm diameter?
    They observed:
    But the images on page 7 (check out the scale what is 200 nm and the size of the bacteria) only show fragments of viral nucleocapsid protein...well maybe the images are just missing...and there are bigger bacteria where it happens...

    SARS-CoV-2 (COVID-19) by the numbers - PMC (nih.gov)
     
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  5. R29k

    R29k MDL GLaDOS

    Feb 13, 2011
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  6. Yen

    Yen Admin (retired)
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    #4267 Yen, May 12, 2022
    Last edited: May 12, 2022
    That makes sense.
    Interesting is that even adults can enhance it (their innate immune cells) by raising body temp = let's have some fever to raise IFN level...
    To raise IFN gamma level also shifts the adaptive immune response to the TH1 (cellular immunity via cytotoxic T cells) pathway...
    Coronavirus | Discussion | Page 153 | My Digital Life Forums


    That's why researchers also say TH1 pathway dominance comes along with more asymptomatic progress....
    So is it the shift to TH1 or enhancement of innate immune cells or both?
    TH1 (cellular immunity via cytotoxic T cells) and TH2 (humoral immunity, antibodies) pathway, both belong to the adaptive immune system, though.

    The innate immune system plays a major role (especially its mucosal defences) and is responsible that kids usually don't get very sick of COVID since it's very active when you are younger...(and kids usually get higher fever, that makes perfectly sense in this regard)...:)

    And that's the major reason why I always said no to vaccination of kids..it actually trains the adaptive immune response (antibodies)...which is a minor system at COVID compared to the active innate system...
     
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  7. gorski

    gorski MDL Guru

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    The deepest knowledge on this subject is in Georgia (former SSSR) - they used viruses against the bacteria, since they didn't have antibiotics....
     
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  8. Yen

    Yen Admin (retired)
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    #4269 Yen, May 16, 2022
    Last edited: May 18, 2022
    Told you so.
    Properly applied science means to stick to scientific rationality despite emotional environments and that comes along with to follow the rules of epidemiology (evolution of virus, probability and survival).

    This is for the so called experts (for instance that UK expert who said "Covid variants may not evolve to be less dangerous") who tried to propagate (fear monger) a virus variant that becomes dominant, is more contagious AND more virulent (dangerous) than the previous variant.

    Omicron BA.1 was already milder than delta and displaced it. Now we have data about the 'second' Omicron sub-variant BA.2 which is displacing the original BA.1.

    "Good news, BA 2 milder than BA 1"


    ZOE COVID Study (joinzoe.com)

    What's the difference between Omicron BA1 and BA2? - YouTube

    Summary of ZOE COVID study presentation


    Edit:

    SARS-CoV-2 vaccination can elicit a CD8 T-cell dominant hepatitis - ScienceDirect

    Not a reactivation, but first study I found related to hepatitis, case study.

    New source added 18/05:
    Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens - ScienceDirect
     
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  9. Yen

    Yen Admin (retired)
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    #4270 Yen, May 17, 2022
    Last edited: May 17, 2022
    A very interesting video.
    A responsible one from the Australian govt., TGA (Therapeutic Goods Administration) gets questioned by Senator Gerard Rennick.

    To my surprise it is very scientific, even goes into biochemistry of mRNA vaccines.

    It's confirming the things I knew already, but it's been difficult to find it for me that time.
    And also many questions remained unanswered, but still..

    They talked for instance what exactly IS different at the mRNA Moderna and Pfizer engineered to the mRNA that would translate exactly 1/1 to the Wuhan spike protein...and much more.

    The differences for instance: Proline modification, stop codons, poly A tail and incorporation of pseudouridine.
    They also talk about the LNP and mRNA half-life...

    My reference to that:

    A must watch for all who want to know more details....a critical questioner.

    "It's not the same Spike Protein and they didn't tell you!"


    They have hidden almost all, even for me it was hard to get info about. (Papers about exact engineering of the mRNA and the LNP around it)...
     
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  10. Yen

    Yen Admin (retired)
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    #4271 Yen, May 22, 2022
    Last edited: May 22, 2022
    New sub-lineages of Omicron are spreading. BA.4 and BA.5
    Omicron on its way to develop further conform to the epidemiological rule for survival. (being endemic)

    https://www.ecdc.europa.eu/en/news-...e-sars-cov-2-omicron-sub-lineages-ba4-and-ba5
    https://www.ecdc.europa.eu/en/covid-19/variants-concern

    AND:
    "First Ever NIH/NIND Study on Vaccine Caused Neurological Injuries (Preprint)"
    https://www.medrxiv.org/content/10.1101/2022.05.16.22274439v1.full-text

    So far so good? NO!
    Check this out:
    If you expand table 4 you'll see patients treated with IVIg (intravenous immunoglobulins) they claim all them have fully recovered!

    But in reality that is NOT true!

    And they waited until May 2022 to publish it.
    Watch this interview with one of the patients.

    She and many more fought to get in a vaccine injury study initiated by US authorities. She tells in detail what happened. The follow up has been suspended, many patients left still vaccine INJURED!
    She also tells what has helped and whatnot. She was in the IVIg group and has NOT fully recovered until today!

    This is sick! A study with a huge delay and lies. Not even there 'they' can be honest and do tell us the truth!
    A beautiful lady who trusted in the vaccines and got badly injured. And not even that, results are false. She speaks for all the vaccine victims.

    The host (Drbeen Medical Lectures) of that video tries to invite more patients of that study.

    If you want to hear another patient interview of vaccine injured people you also can search for Shaun Barcavage on his (Drbeen Medical Lectures) channel. Shaun is a fantastic healthcare professional.



    BTW: I had a look at an ongoing German study about vaccine adverse events.
    The pre-release of results are confirming the percentage of SEVERE vaccine injuries found at the Nordic European country studies.
    0.8%!!!!!!!!!
    Means 8 people of 1000 who got vaxxed suffer from SEVERE adverse events!

    The official number here is 0.02% This is a joke!
     
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  11. Mr.X

    Mr.X MDL Guru

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    #4272 Mr.X, May 22, 2022
    Last edited: May 22, 2022
    And those not injured or having any symptom of adverse effects so far, it's result of getting placebo only. Just my theory.
     
  12. case-sensitive

    case-sensitive MDL Expert

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    ' Strange ' .........,..,.. this thread is absolutely ' irelevant ' , its a ' kindergarten ' and its a conspiracy theory thread from the start to the finish .......... but it doesnt get deleted ;)

    I ' wonder why ' ;)
     
  13. Mr.X

    Mr.X MDL Guru

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    Because you are wrong. Awfully wrong. Plenty of scientific evidence here but you don't want to acknowledge it.
     
  14. Mr.X

    Mr.X MDL Guru

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    Btw I think you haven't seen this thread of mine lol
    https://forums.mydigitallife.net/threads/poxvirus-discussion.85385/

    And btw your thread was removed but there's news for you here, second video: https://forums.mydigitallife.net/threads/chlorine-dioxide.82491/page-16#post-1728811
     
  15. Yen

    Yen Admin (retired)
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    #4276 Yen, May 27, 2022
    Last edited: May 29, 2022
    This study now examined how vaccines protect from getting long COVID, a long desired insight...
    This is the first time this subject has been examined and you see a huge study power n (means lots of peoples included).
    https://www.nature.com/articles/s41591-022-01840-0


    Briefly:
    Compared: People who are not vaccinated and got COVID and then the probability to get long COVID versus people who got vaccinated, then COVID (vaccine failure or the so called breakthrough infection, BTI) and then the probability to get long COVID.

    Only 15% less (HR= 0.85). The vaccines do only protect you by 15% from getting long covid compared to somebody who had not the vaccine.

    Secondly vaccination does not change the 'severity and appearance' of long COVID means has no effect on which organs are affected. It does not 'eradicate' a certain symptom of long COVID, anything that one can have when getting long covid a vaxxed one still can get...

    mRNA vaccines were better than vector virus based vaccines. Means AZ and J&J were poorer (Average of all as being said only 15%, though).

    And they also found protection from death is HR=0.66. Means the probability to die from covid is 34% less when being vaxxed and having a BTI.

    As a summary (added the new percentage found by Prof. Matthes and from another study) we can now list risk and benefits of the vaccines how they 'really' are. We have now a solid bunch of data after this period of time:

    Risk: Severe adverse events in relation to vaccination: 0.8% (8 out of 1000). Source: Charité Berlin, Prof. Matthes.
    Another study, more detailed:
    https://www.sciencedirect.com/science/article/pii/S1201971221003581

    People still are getting infected by another variant, the so called breakthrough infections and people still do infect others. Zero protection from getting infected after several months of last shot due to waning, shortens the period of extension the more shots you have had already. (At 4th several weeks only. Israel study posted already).

    Benefit:
    From getting long COVID 15%
    From death 34%
    OK you might want to mention from severe progresses also. Yes that's right.
    But this is not an extra subject of the study. So lets simply follow rationality. Those who still die from covid despite vaccination must have been also severe before.
    And IF you say long covid can be considered as being severe then it's also 15% only.

    So tell me. Are the vaccines as they have s(t)old you?
    Protection from fatal outcome? I mean we 'only' have 34% less deaths than we would have without vaccines!
    So every death is one too much, so here well OK...

    Protection from long COVID? Only 15% less people, means long COVID will affect us years IF we do not develop therapies / treatments / drugs against it!
    Severe vaccine injuries? Extrapolate that 8 out of 1000 to the population who got vaxxed!

    Sure the numbers can change, but not much amymore. They have a very sold database...

    If you want a guided explanation of the study:


    If you don't trust any 'guidance' ignore this video and my comments and make your conclusions directly from the paper.
     
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  16. Palladin

    Palladin MDL Senior Member

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    #4277 Palladin, Jun 3, 2022
    Last edited: Jun 3, 2022
  17. Yen

    Yen Admin (retired)
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    The article has no source posted, which actually belongs to serious journalism. It's a copy and paste which is going around ATM.
    Novavax hasn't been approved yet by the FDA and the FDA is in the process of approval...here at EU it has got EUA already...

    Myocarditis and pericarditis are serious issues. Severe or fatal, never mild. So it makes perfectly sense to have a close look at them.
    I did some research and think they refer to this study:
    https://www.nejm.org/doi/full/10.1056/NEJMoa2116185

    So to answer your question:
    Around 20,000

    But you won't find there anything about heart issues. So I dug a bit deeper:
    https://www.nejm.org/doi/suppl/10.1056/NEJMoa2116185/suppl_file/nejmoa2116185_appendix.pdf

    Hint for everybody: Always have a look at supplementary indexes of a study!
    Usually you won't find details, especially negative details on the main papers.

    Search there for Cardiac disorders and you'll find even more cases.

    My take on this:
    Studies before already indicated that heart related issues come from the antigen itself (Spike).
    So you also find heart related issues at COVID itself....

    This means it is COVID vaccine related, not type of vaccine related. Most if not all COVID vaccines either contain the spike protein or a blueprint for it as an antigen. (AFAIK only one or two not yet approved candidates have other antigens)...

    What is the difference at occurrence of heart issues anyway:

    -At genetic vaccines such as mRNA and vector virus vaccines you never know the actual dose of the antigen produced. They instruct your body to make it. The dose of the genetic blueprint is of course defined, but not the production rate. So if you have a productive machinery you make more of it than another one.

    -Biodistribution. The big WHERE. Where is it made and to where travels it.
    At genetic vaccines it is always made within a human cell.

    At Novavax you always administer a defined dose of the antigen itself and always directly into the deltoid muscle.

    I already mentioned. To use the s protein as the antigen was not the best idea.
    It was expectable that Novavax will also cause heart related issues since we know the s protein can travel a lot...although since the dose is exactly defined it should lead to a more consistent rate, probably lower on average compared to Moderna or Pfizer...

    Since all the vaccines do not protect you from getting infected (sooner or later) I'd consider any heart related issue of vaccines as additional risk only. (The virus itself comes with the s protein anyway)....
     
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  18. Palladin

    Palladin MDL Senior Member

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    #4279 Palladin, Jun 4, 2022
    Last edited: Jun 4, 2022
    Yen:
    Thanks for the thorough analysis. It always amazes me how the MSM almost always fails to report all the facts, instead it relies on only reporting whatever hysteria that might generate the most reactions.

    Had the media said something like this....In a trial by Novavax the FDA discovered that 5 of the 20,000 patients had some sort of heart related adverse reactions. What do you think the reaction to that headline would be. Crickets probably.

    Then there's the Monkey Virus hysteria. I can't find it now, but there was a table published that listed 23 Countries and the total cases of Monkey Virus cases was 250. That equates to a bit more than 10 per COUNTRY, not cities, COUNTRY. And there were, zip, zero, nada fatalities in those 23 COUNTRIES.

    Here's something I put together back in April 2022 showing the Covid-19 deaths by percentage of population by state in the US.
     

    Attached Files:

  19. Yen

    Yen Admin (retired)
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    #4280 Yen, Jun 4, 2022
    Last edited: Jun 4, 2022
    Heart related issues or cardiac disorders are generic terms. Both actually describe a set of symptoms / illnesses.

    Myocarditis is inflammation of the heart muscle, pericarditis inflammation of the pericardium (heart sac) which is a protective layer around it.
    And they list myocardial infarction, which is known as heart attack caused by a blocked artery.
    There was no pericarditis at that study.

    Those 3 are mentioned frequently since they are severe for sure.
    The tissue gets damaged due to inflammation and / or undersupply of blood. The body tries to repair it usually by creating new tissue. But some 'places' might get left-out and the new tissue usually has a different physics since it is scar tissue.
    At critical condition you need to get hospitalized / surgery.


    It can lead to different physics and performance of the heart which can be imaged by heart MRT. The physical performance additionally via ECG. Some leftovers can be permanent (damage).

    If you summarize Novavax vaccine has caused 10 cases versus placebo 6. (Table S16)
    They list 3 age groups each, but the placebo groups are smaller. The relative percentages now are quite similar so the vaccine doesn't look really worse than placebo.

    What's odd is the fact that the heart related issues found at placebo are way over average of what usually happens at the population (corresponding age groups). THIS is the point I am struggling with.

    Vaccine development.
    If I have to develop new COVID vaccines I'd use the RBD as an antigen, perfectly a mixture of those which represent current variants. If possible rather a nasal application.

    Monkey pox:
    There had been small outbreaks at several countries all the time before. Besides of that it is endemic in Central African Republic, the Democratic Republic of the Congo etc....

    This is nothing special, but now due to COVID it gets hyped at any MSM.
    It has been discovered in monkeys first, although it actually does not spread within monkeys. It rather does in rodents and jumps from there. (Zoonosis).


    It's not contagious IF you know the way it gets transmitted. You need close physical contact to the infectious fluids which are found within the blisters on the skin, lesions and contaminated materials such as bedding.

    You need to get into quarantine for 25 days. Masks are BS. You have to protect yourself when caring about an infected person. (Avoid direct contact to those fluids / bedding)

    There are two clades of monkeypox virus: The West African clade and the Congo Basin (Central African) clade. The latter is the one that is more dangerous, but so far only the West African clade has spread.

    Monkey pox is usually a self-limiting disease due to its way to spread.
     
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